Tantalum also has excellent chemical properties, with very high corrosion resistance, both in cold and hot conditions, and does not react to hydrochloric acid, concentrated nitric acid and aqua regia. However, tantalum can be corroded in hot concentrated sulfuric acid, below 150 degree , tantalum will not be corroded by concentrated sulfuric acid, only at temperatures higher than this temperature will have a reaction, at 175 degree in concentrated sulfuric acid for 1 year, the thickness of the corrosion of 0.0004 mm, tantalum will be put into 200 degree of sulfuric acid immersion for one year, the surface layer of the damage is only 0.006 mm. At 250 degree , the corrosion rate increased, for each year was corroded thickness of 0.116 mm, at 300 degree , was corroded more quickly, immersed in 1 year, the surface was corroded 1.368 mm. In fuming sulfuric acid (containing 15% of SO3) corrosion rate than in concentrated sulfuric acid is more serious, at 130 degree in this solution immersed in 1 year, the surface was corroded thickness of 15.6 mm. Tantalum will also be corroded by phosphoric acid at high temperature, but the reaction generally occurs above 150 degree , at 250 degree in 85% phosphoric acid, immersed in 1 year, the surface was corroded 20 mm, in addition, tantalum in the mixed acid of hydrofluoric acid and nitric acid can be dissolved quickly. But tantalum is more afraid of strong alkali, in 110 degree 40% concentration of caustic soda solution, tantalum will be quickly dissolved, in the same concentration of potassium hydroxide solution, as long as 100 degree will be quickly dissolved. In addition to the situation described above, general inorganic salts can not generally corrode tantalum below 150 degree . Experiments have proved that tantalum at room temperature, alkali solution, chlorine, bromine, dilute sulfuric acid and many other agents are not effective, only in hydrofluoric acid and hot concentrated sulfuric acid reaction. Such a situation is relatively rare in metals.

Tačiau, at aukšta temperatūra, the oxide film on the surface of tantalum is destroyed, so it can react with a variety of substances, and at room temperature tantalum can react with fluoru. At 150 laipsnis , tantalas is inertiškas to chloras bromas jodas, at 250 laipsnis , tantalas is nejudantis korozija atsparus to sausas chloras, in the chloras turintis vanduo garai šildomas to 400 laipsnis , can still palaikyti the bright, at 500 degree is beginning to be corroded, at 300 degree above tantalas ir bromas reakcija, jodas garai kada kada temperatūra pasiekia the red heat prieš are inertiška. Vandenilis chloridas reaguoja su tantalu at 410 laipsnis to produkcija pentachloridas, ir vandenilis bromidas reacts with tantalas at 375 laipsnis . Siera reaguoja su Ta kai šildoma to 200 laipsnis arba žemesnis, ir anglis ir angliavandeniliai react with Ta at 800-1100} degree .